Cold-Formed Pharmaceutical Foil

High-Seal & Safety Material for Premium Drug Packaging Cold-formed pharmaceutical foil is a critical packaging material for high-end pharmaceuticals, offering unmatched **barrier performance**, **cold-formability**, and **food-grade safety** to protect drugs from moisture, oxygen, and light. As a core material in blister packaging for tablets, capsules, and injectables, it addresses the strict requirements of the pharmaceutical industry for product stability and shelf life. Henan Mingtai Aluminum Co, Ltd. (stock code: 601677), a leading aluminum processor with 26+ years of expertise, specializes in producing cold-formed pharmaceutical foil (8021-O, 8079-O alloys) that meets global standards, making it a trusted supplier for pharmaceutical packaging enterprises worldwide.

1. Core Advantages of Mingtai’s Cold-Formed Pharmaceutical Foil

Mingtai’s cold-formed pharmaceutical foil is engineered to solve key challenges in drug packaging, delivering four critical benefits:

●Superior Multi-Barrier Performance to Extend Drug Shelf Life: Drugs are highly sensitive to external factors—moisture can cause clumping, oxygen leads to oxidation, and light degrades active ingredients. Mingtai’s 8021-O cold-formed foil features a dense metallic structure with pinhole density ≤1 piece/m² (diameter ≤0.03mm), blocking 99.9% of oxygen and reducing moisture transmission rate to ≤0.1g/(m²·24h). It also provides complete light shielding (UV transmittance = 0%), extending drug shelf life by 2-3 times compared to traditional PVC packaging.

●Excellent Cold-Formability for Complex Blister Designs: High-end drugs often require custom blister shapes (e.g., irregular cavities for multi-dose tablets). Mingtai’s cold-formed foil (O temper) has an elongation rate of 15-20% and a cupping value ≥7.5mm, enabling it to be cold-formed into deep cavities (depth ≥8mm) without cracking or wrinkling. This flexibility supports diverse packaging needs, from small-dose capsules to large-volume injectable containers.

●Food-Grade Safety & Strict Quality Compliance: Direct contact with drugs demands the highest safety standards. Mingtai’s cold-formed pharmaceutical foil complies with FDA 21 CFR 175.300, EU 10/2011, and Chinese GB/T 25591 standards, with heavy metal content ≤0.25ppm and surface oil content ≤5mg/m². It undergoes 100% ultrasonic flaw detection and microbiological testing, ensuring no contamination or toxic residues—critical for pharmaceutical applications.

●Strong Heat-Seal Strength & Durability: The foil’s surface is optimized for adhesion with adhesives, achieving a heat-seal strength ≥3N/15mm (per ASTM F88). This ensures tight sealing even under temperature fluctuations (-40°C to 60°C) during transportation and storage, preventing drug leakage or contamination. Its corrosion resistance also eliminates degradation from contact with acidic/alkaline drugs.

2. Key Specifications & Alloy Selection for Cold-Formed Pharmaceutical Foil

Mingtai offers tailored solutions for different pharmaceutical packaging needs, with core parameters and alloy options optimized for performance:

Alloy Types & Application Scenarios

Technical Specifications

●Width: 100-1700mm (customizable to match blister machine sizes)

●Surface Quality: No black spots, scratches, pinholes, or “lotus leaf edges”; brush test grade = A (water wettability ≥32 dynes/cm)

●Mechanical Properties: Tensile strength = 100-130MPa (O temper); elongation rate ≥15%

●Compliance Standards: ISO 15754 (pharmaceutical packaging), USP Class VI (biocompatibility), and CNAS laboratory certification

3. Production Process of Mingtai’s Cold-Formed Pharmaceutical Foil

Mingtai adheres to a strict 8-step production process to ensure consistent quality, aligning with global pharmaceutical manufacturing standards:

●Billet Inspection: Strictly test aluminum alloy billets (8021/8079) for chemical composition and internal defects to eliminate substandard raw materials.

●Cold Rolling: Use CVC 6-roller cold rolling mills to reduce billet thickness to 0.025-0.08mm, controlling roll roughness (Ra = 0.2-0.4μm) to ensure surface smoothness.

●Intermediate Rolling: Conduct multi-pass rolling to refine grain structure, enhancing the foil’s cold-formability and barrier performance.

●Coil Combining: Combine multiple thin foils to achieve the required thickness, ensuring uniform layer adhesion.

●Slitting: Use precision slitting machines to cut coils into required widths, ensuring neat edges with no burrs or “lotus leaf edges”.

●Annealing: Heat the foil to 300-350°C in a vacuum furnace for 4-6 hours to eliminate internal stress, improve ductility, and remove residual rolling oil (ensuring oil content ≤5mg/m²).

●Quality Control: Perform 100% inspections, including pinhole detection (ultrasonic), mechanical property testing (tensile/elongation), and surface defect checks (visual + machine vision).

●Moisture-Proof Packaging: Seal finished foil in aluminum-plastic composite bags with desiccants to prevent oxidation and moisture absorption during storage and transportation.

4. Mingtai Aluminum: Trusted Supplier of Cold-Formed Pharmaceutical Foil

Mingtai’s production capabilities and quality control systems make it a preferred partner for pharmaceutical packaging:

●Pharmaceutical-Grade Production Lines: Equipped with domestic-first “1+4” hot rolling lines, precision foil rolling machines, and vacuum annealing furnaces, Mingtai ensures ultra-low pinhole density and uniform thickness (tolerance ±0.002mm). The clean workshop (Class 10000) meets GMP standards for pharmaceutical packaging materials.

●Rigorous Quality Assurance: With 600+ professional technical personnel and a CNAS-accredited testing center, Mingtai conducts comprehensive tests—including heavy metal analysis (ICP-MS), microbiological testing, and cold-forming simulation—to ensure compliance with global standards. Each batch is accompanied by a detailed mill test certificate (MTC) for traceability.

●Custom Solutions & Efficient Supply: Mingtai supports customized thicknesses, widths, and surface treatments (e.g., enhanced adhesion coating) to match specific drug packaging needs. It maintains 0-3 tons of spot inventory for urgent orders and delivers large-scale orders (10-500 tons) within 3-30 days, supported by 5 production bases and global logistics partnerships.

5. Why Mingtai’s Cold-Formed Pharmaceutical Foil Outperforms Alternatives

Compared to traditional PVC blisters and other aluminum foils, Mingtai’s product offers distinct advantages:

●Better Barrier Than PVC: PVC allows moisture and oxygen transmission, reducing drug shelf life; cold-formed aluminum foil’s barrier performance is 50-100 times superior, ideal for high-sensitivity drugs.

●More Formable Than H-Temper Foil: H-temper aluminum foil is rigid and prone to cracking during cold forming; Mingtai’s O-temper foil balances flexibility and strength, supporting complex blister designs.

●Safer Than Non-Certified Foil: Uncertified foil may contain heavy metals or residual oil; Mingtai’s product meets global pharmaceutical safety standards, eliminating health risks for patients.

Contact Mingtai for Cold-Formed Pharmaceutical Foil

If you’re a pharmaceutical packaging enterprise seeking high-quality cold-formed pharmaceutical foil, Mingtai Aluminum provides reliable, compliant solutions. Our technical team offers free sample testing and customized recommendations based on your drug type and packaging requirements.

Whatsapp/Wechat: +86-17760728273

Website: www.mingtai-al.com